Dual-Integrin αvβ3- and Gastrin-Releasing Peptide Receptor–Targeting PET Radiotracer (68Ga-BBN-RGD)
نویسندگان
چکیده
منابع مشابه
68Ga-BBN-RGD PET/CT for GRPR and Integrin αvβ3 Imaging in Patients with Breast Cancer
Purpose: This study was to assess a gastrin-releasing peptide receptor (GRPR) and integrin αvβ3 dual targeting tracer 68Ga-BBN-RGD for positron emission tomography (PET)/computed tomography (CT) imaging of breast cancer and metastasis. Materials and Methods: Twenty-two female patients were recruited either with suspected breast cancer on screening mammography (n = 16) or underwent breast cancer...
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INTRODUCTION The gastrin-releasing peptide receptor (GRPR) is overexpressed in breast cancer. The present study evaluates GRPR imaging as a novel imaging modality in breast cancer by employing positron emission tomography (PET) and the GRPR antagonist (68)Ga-RM2. METHODS Fifteen female patients with biopsy confirmed primary breast carcinoma (3 bilateral tumors; median clinical stage IIB) unde...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2017
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.117.191478